Clinical Study on Treating Polycystic Ovary Syndrome of Liver ...

[Abstract]

Background:Polycystic ovary syndrome is the most common gynecological endocrine diseases of women of childbearing age. With irregular menstruation (infrequency, less, amenorrhea, dysfunctional uterine bleeding), hirsutism, obesity, acne, infertility, hyperlipidemia, hyperandrogenism, insulin resista-nce and chronic anovulation as the main clinical feature. Western Medicine is mainly to promote the ovulation, establishment of artificial menstrual cycle, to stop pilosis polytrichia and method of prevention of endometrial cancer. Clomiphene ovulation induction has a high rate of ovulation on the patient of fertility requirements, but easily lead to luteal insufficiency, ovarian hyperstimulation syndrome, luteinized unruptured follicle syndrome These pregnant women are prone to causing miscarriage, in the side of menstrual cycle adjustment, it has poor long-term efficacy and more side effects, Chinese Medicine treatment of PCOS has a good effect, in patients with reproductive endocrine disorders can be reversed state, menstruation and help pregnant, and has significant long-term efficacy?less side effects, however, a single treatment with Traditional Chinese Medicine there is often a treatment cycle is long, slow markedly, the drawbacks of poor patient compliance. TCM-WM therapy, reducing the side effects of western medicine alone, but also shorten the time of pure Chinese Medicine treatment. Integrative medicine clinical research will become one of the hot.Object ive:With a randomly comparison observation on the curative effective about treating PCOS of liver depression with adjustment of Jia Jian Xiao Yao San and Chloramiphene.Methods:Choice60gynecology clinic patients from March2010to April2011who have fertility requirements in our hospital in line with diagnosis of PCOS in Western Medicine and in line with diagnosis of PCOS of liver depression in Chinese Medicine as the tested object. Using random numbers randomly divided into test group and control group30patients separately, test group on the basis of Clomiphene citrate ovulation, plus the adjustment of Jia Jian Xiao Yao San, control group were treated for ovulation induction Clomiphene, were treated for three menstrual cycles, keeping observation on each group, keeping Observation on the improvement of symptoms such as endocrine changes in circumstances?ovulation?cervical mucus changes of each group before and after treatment period. Investigate the Clinical Effect of PCOS of liver depression treatment by the adjustment of Jia Jian Xiao Yao San combined Clomiphene citrate therapy.Results:1?Two clinical total effective rate comparison:the treatment group clinical total effective rate was86.67%, the control group total effective rate was56.67%, after a statistical analysis of clinical efficacy had significant difference(p<0.05), shows the clinical efficacy of the treatment group than the control group.2?Improvement in symptoms related to Traditional Chinese medicine of two groups of patients:TCM symptom score after treatment, after t-test, treatment of a cycle is not significantly different (p>0.05).after two cycles of treatment there was significantly different (p<0.05), after treatment of three cycles there was very significantly di fference (p<0.01). Description of the menstrual cycle and medical symptoms improve, the treatment group better than the control group.3?Observation on BBT:two groups of patients after treatment compared to treatment, after three cycles no significant difference(p>0.05).4?Comparison of the situation of ovulation of the two groups of patients after treatment, With the X2test, after three treatment eyeles, thero is a significant difference (p<0.05)5?Comparison of the situation of ovulation of the two groups of patients after treatment. Description of the CS improve, the treatment group better than the control group.6?After treatment, description of the prolactin improve of the test group is better than the control group; description of the T improve of the test group is not better than the control group.Conclusion:Under normal circumstances, the liver-qi harmonizing and giving free passage?srretch?declared scattered, distribution, tirle burner unobstructed the coordination function of various organs is a prerequisite for pregnancy. Modern life and work pressure, creates the common cause of the stagnation of liver-qi. Found in clinical because most patients of polycystic ovary syndrome usually menstrual disorders, infertility, women of childbearing age married for a long time infertility will appear depression, anxiety, low self-esteem and other symptoms. Performance the symptoms of the stagnation of liver-qi, through observation and comparison, the results show that the treatment group improved in all aspects of patients than the control group, As the subject of time and sample size limitations, having not made evidence of flavored Jia Jian Xiao Yao San combined Clomiphene improve pregnancy rate in PCOS is better than Clomiphene citrate group, but as a combination therapy clinical thinking of gynecological diseases, worthy of further exploration extension.

Title: Clinical Study on Treating Polycystic Ovary Syndrome of Liver Depression with Adjustment of Jia Jian Xiao Yao San and Chloramiphene

Category: Liver Cancer

Filename: Clinical Study on Treating Polycystic Ovary Syndrome of Liver Depression with Adjustment of Jia Jian Xiao Yao San and Chloramiphene.pdf

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